Active substance: Ivermectin
There are currently no vector control tools in the GMS that specifically target outdoor feeding Anopheles which is a major impediment for malaria vector control in the region.
Novel vector control tools that target outdoor malaria transmission are urgently needed to support artemisinin resistance containment and malaria elimination efforts in the GMS.
Ivermectin has been shown to be lethal to over a dozen Anopheles species worldwide.
It is one of the few vector control measures that targets outdoor malaria transmission. Laboratory studies, clinical trials, and field studies demonstrate that ivermectin is lethal to Anopheles gambiae at human relevant concentrations.
In addition to direct mosquito-lethal effects, ivermectin suppresses development of P. Plasmodium transmission in the GMS is complex with numerous Anopheles species serving as primary and secondary vectors throughout the region.
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