Active substance: Doxycycline
The source of infection appears to be unclear in all cases. In two patients with a tentative diagnosis of sepsis, the strain was isolated from the blood.
One strain was isolated from cerebrospinal fluid of a patient with cerebral pseudotumor, one was isolated from a wound infection following elective orthopedic surgery, and one was isolated from bone with signs of osteomyelitis.
The six reported cases had no common predisposing condition. One patient had a variable immunodeficiency, and one patient had an end-stage renal disease secondary to diabetic nephropathy and hypertension.
No underlying medical conditions were known in the other four patients. In our patient.
The sources of the infection are unknown in all reported cases. In one patient, abscessed teeth were suspected to be the source, suggesting that M.
In our patient, it is likely that the contamination with this organism occurred in Nigeria, possibly while swimming in a lake. Indeed, there is a growing body of evidence that M.
Furthermore, the isolation from soil samples of phenanthrene-degrading 3, protease-producing 5, and N-acyl homoserine lactone-producing strains 14 related to the genus Massilia, as well as four species of the genus Massilia isolated from different soil samples from southeast China 17, 18, confirms the environmental nature of the species.
Recently, other Massilia strains have been isolated from air 11 — 13 and drinking water 6. Malaria is widespread in tropical and subtropical regions, including parts of Africa, Asia, and Latin America.
Keep taking the medicine, but talk to your doctor or pharmacist if these side effects bother you or don't go away: headaches feeling or being sick nausea or vomiting being sensitive to sunlight Serious side effects are rare and happen in less than 1 in 1,000 people.
In rare cases, doxycycline can cause a serious allergic reaction anaphylaxis.
These are not all the side effects of doxycycline. For a full list see the leaflet inside your medicines packet.
Information: You can report any suspected side effect to the UK safety scheme. How to cope with side effects What to do about: headaches - make sure you rest and drink plenty of fluids. Everyday painkillers, such as paracetamol and ibuprofen, are safe to take with doxycycline.