Active substance: Hydroxyzine
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It can be taken with or without food. Its absorption does not increase when taken with food, but doing so can help prevent nausea. Nausea is often caused when the 5 HT 3 receptors actively absorb free serotonin, as this receptor is present within the digestive tract.
This side effect, if present, should subside as the body adjusts to the medication.
Received Jan 1; Accepted Jan 29. This article has been cited by other articles in PMC. Abstract Pharmacotherapy for insomnia in primary care settings can be challenging.
Frequently, there are multiple coexisting medical and psychiatric conditions, drug interactions, concern regarding use of habit-forming sleep aids, and paucity of time in office visits to discuss management of sleep difficulties.
This article reports the results of a literature search related to pharmacotherapy for insomnia and presents 4 clinical vignettes with corresponding treatment options.
Adequate sleep is necessary for normal function and is essential for physical and psychological health. Chronic insomnia is associated with impairments in many aspects of interpersonal difficulties, quality of life, substance abuse, cognition, risk of psychiatric disease, work-related problems, and accident proneness.
Approximately one-third of all people will suffer from chronic insomnia at some point in their lifetime, and one-tenth of them will have significant daytime impairment as a result.
Problem sleep is a prominent symptom of many somatic and emotional illnesses. The definitions and diagnoses of insomnia vary widely. The term insomnia has various medical meanings, as either a symptom or a specific disorder.
According to DSM-5 criteria, 2 insomnia is concern about poor sleep quantity or quality with 1 or more of the following: difficulty getting to and staying asleep, early awakenings followed by trouble returning to sleep, and personal distress or daytime dysfunction.
Insomnia cannot be attributed to a substance abuse or primary sleep disorder and is not explained by a coexisting medical or psychiatric disorder. The sleep difficulty must be present despite adequate opportunity for sleep, must occur at least 3 nights per week, and must be present for at least 3 months.
The most important aspect of an insomnia evaluation is to obtain a thorough sleep history. A complete evaluation for insomnia includes assessing the physical and psychiatric conditions associated with sleep difficulties, as well as environmental and social factors or personal concerns.
Always consider substance use, coexisting pathology, other sleep disorders, and medications or other agents eg, caffeine that cause insomnia.
Sleep hygiene might be one consideration, which includes teaching habits and behaviors that aim to induce a better nighttime sleep.